Maple-Glazed Chicken Thighs with Roasted Brussels Sprouts

If fall had a flavor, it might just be this. Savory roasted chicken glazed with pure maple syrup and Dijon, caramelized Brussels sprouts, and the kind of aroma that fills your home with warmth.

This Maple-Glazed Chicken Thighs with Brussels Sprouts recipe is everything you want in a fall dinner: fast, flavorful, and full of gut- and hormone-supportive nutrients. It’s high in protein and fiber, naturally gluten- and dairy-free, and made with anti-inflammatory ingredients that stabilize blood sugar and keep energy steady.

Whether it’s meal prep Sunday or a cozy weeknight, this dish makes healthy eating taste like comfort food.

Ingredients (Serves 4)

For the Chicken & Glaze:

• 1 ½ lbs boneless, skinless chicken thighs

• 2 tbsp pure maple syrup

• 1 tbsp Dijon mustard

• 2 tbsp coconut aminos (or tamari)

• 1 tbsp apple cider vinegar

• 2 garlic cloves, minced

• 1 tbsp olive oil or avocado oil

• ½ tsp smoked paprika

• Sea salt and black pepper, to taste

For the Brussels Sprouts:

• 1 lb Brussels sprouts, trimmed and halved

• 1 tbsp olive oil or avocado oil

• Sea salt and pepper, to taste

Instructions

1. Preheat oven to 400°F (200°C) and line a baking sheet with parchment paper.

2. Whisk the glaze: In a small bowl, combine maple syrup, Dijon mustard, coconut aminos, apple cider vinegar, garlic, olive oil, smoked paprika, salt, and pepper.

3. Marinate: Place chicken thighs in a shallow dish or bowl and pour half of the glaze over them. Toss to coat and let sit while prepping Brussels sprouts.

4. Prep the veggies: Spread Brussels sprouts on one side of the baking sheet. Toss with olive oil, salt, and pepper.

5. Add the chicken: Place chicken thighs on the other side of the sheet pan and brush with extra glaze.

6. Roast: Bake for 25–30 minutes, flipping chicken halfway through and brushing with remaining glaze.

7. Finish: Broil for the last 2–3 minutes if you like caramelized edges.

Serve warm — drizzle any leftover pan glaze over the chicken and veggies before serving.

Functional Health Benefits

• Protein for hormone production: Chicken provides amino acids needed to create and balance estrogen, progesterone, and cortisol.
• Cruciferous veggies for estrogen detox: Brussels sprouts are rich in sulforaphane and indole-3-carbinol, compounds that help the liver process and eliminate excess estrogen.
• Maple syrup for mineral balance: A natural sweetener that contains zinc and manganese, which support thyroid and blood sugar health.
• Garlic and apple cider vinegar help regulate insulin and support the microbiome.

Together, this meal delivers a perfect balance of protein, fat, and fiber which is the trifecta for hormone and gut balance.

Tips for Success

• Double the recipe for meal prep — it reheats beautifully.

• Add roasted sweet potatoes or quinoa for a more filling meal.

• For extra flavor, sprinkle with fresh thyme or rosemary before baking.

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Xo,

Dr Sheena